皮肤创面无机诱导活性敷料治疗股静脉导管置管穿刺点感染的疗效观察

Efficacy Observation of Dermlin in the Treatment of Femoral Venous Catheter Site Infection

目的:比较皮肤创面无机诱导活性敷料和莫匹罗星软膏治疗股静脉导管置管穿刺点感染的疗效及安全性。方法:将92例股静脉导管置管穿刺点感染患者随机分为试验组(46例)与对照组(46例),试验组给予皮肤创面无机诱导活性敷料换药,对照组给予莫匹罗星软膏换药。比较两组临床疗效及药品不良反应的差异。结果:试验组治愈时间为(7.88±0.79)d,显著低于对照组的(9.26±0.91)d(P<0.01);试验组显效率为82.61%,显著高于对照组的56.52%(P<0.05);试验组不良反应发生率为8.70%,显著低于对照组的30.43%(P<0.01)。结论:皮肤创面无机诱导活性敷料治疗股静脉导管置管穿刺点感染的疗效优于莫匹罗星软膏,不良反应少。

OBJECTIVE： To compare the therapeutic efficacy and safety of Dermlin and Mupirocin ointment in the treatment of femoral venous catheter site infection. METHODS： 92 patients with femoral venous catheter site infection were randomly divided into test group and control group with 46 cases in each group. Test group received treatment of Dermlin, while control group re- ceived treatment of Mupirocin ointment. Clinical efficacy and adverse drug reaction were compared between 2 groups. RESULTS： The healing time of test group [（7.88 ± 0.79）d] was significantly lower than [（9.26 ± 0.91）d] of control group （P〈0.01） ; the effec- tual rate of test group （82.61%） was significantly higher than 56.52% of control group （P〈0.05） ; the incidence of ADR （8.70%） in test group was significantly lower than 30.43% in control group （P〈0.01）. CONCLUSIONS：Dermlin is better than Mupirocin ointment and has a little adverse drug reaction in the treatment of femoral venous catheter site infection.