我院189例药品不良反应报告分析

Analysis of 189 Adverse Drug Reaction Reports in Our Hospital

目的:了解我院药品不良反应(ADR)发生的一般规律和特点,为临床合理用药及正确评价ADR的发生提供参考。方法:对我院2012年所收集的189例ADR进行回顾性分析。结果:在189例报告中,男性(108例)多于女性(81例),以≥50岁的老年人与≤18岁的未成年人发生率居高;在给药方式中,静脉滴注引发的ADR占61.90%;ADR累及器官或系统以皮肤及其附件最为常见,有78例(41.27%)。结论:临床应加强ADR监测工作,以规范临床合理用药,确保患者用药安全。

OBJECTIVE： To analyze the general regularity and characteristics of adverse drug reaction （ADR） in our hospital and to supply references for rational drug use and correct evaluation of ADR. METHODS： 189 ADR reports in our hospital in 2012 were analyzed retrospectively. RESULTS： Among 189 ADR cases, the number of male （108 cases） was more than female （81 cas- es）. The incidence of ADR was significantly higher in the elderly aged ≥50 and juveniles aged ≤18. 61.90% of ADR were in- duced by intravenous drip. The main clinical manifestation of organs or systems involved in ADR were lesion of skin and its appen- dants, which involved 78 cases （41.27 % ）. CONCLUSIONS： ADR monitoring should be strengthened, so as to standardize clinical rational drug use and ensure the safety of drug use.