2Honggang Zhu,S.Kevin Li.Improvement on conventional constant current DC iontophoresis:a study using constant conductance AC iontophoresis[J].Int.pharm,2002,82(2～3):249～260
3Yamamoto T,Yamamoto Y.Electrial properties of the epidermal stratum corneum[J].Med Biol Eng Comput,1976,14(2):151
4Inada H,Ghanem AH,Higuchi WI.Studies on the effects of applied voltage and duration on human epidermal membrane alteration/recovery and the resultant effects upon iontophoresis[J].Pharm Res.,1994,11(5):687
5Riviere JE,Monteim Riviere NA,Rogers RA,et al.Pulsatile transdermal delivery of LHRH using electroporation:Drug delivery and skin toxicology[J].J Control Release,1995,36(3):229～237
6Anthony C,Geraci DO,Jouathan S,et al.Topical Steroids:Dosing Forms and General Considerations[J].Hospital Pharmacy,1991.26～699
7R.Vanbever,N.Lecoutuier,V.Preat.Transdermal Delivery of Metoprolol by Electroporation[J].Pharm.Res.,1994,11(11):1657～ 1662
8Y.Song,S.K.Li,K.D.Peck,et al.Human epidermal membrane constant conductance iontophoresis:alternating current to obtain reproducible enhanced permeation and reduced lag times of a nonionic polar permeant[J].Int,Pharm,2002,232(1～2):55～56
9孙伟人.单片微型计算机原理及其应用[M].北京:清华大学出版社.1989.
10Vanbever R,Lecoutuier N,Preat V. Transdermal Delivery of Metoprololby Electroporation[J]. Pharm Res, 1994,11 ( 11 ) : 1 657-1 662.
