林茜草化学成分的研究

Studies on the Chemical Constituents of the Root of Rubia sylvatica

从林茜草 Rubia sylvatica中首次分得 11个化合物 ,经理化常数和光谱分析 ,分别鉴定为 5 -羟基 -萘并 [1,2 - b]呋喃 - 4-羧酸甲酯 ( )、大叶茜草素 ( )、1-羟基 - 2 -甲基蒽醌 ( )、β-谷甾醇 ( )、胡萝卜苷 ( )、1,3,6 -三羟基 -2 -甲基 -蒽醌 - 3- O- (6′-乙酰基 )新橙皮糖苷 ( )、1,3,6 -三羟基 - 2 -甲基蒽醌 - 3- O新橙皮糖苷 ( )、萘酸双糖苷 ( )、1,3,6 -三羟基 - 2 -甲基蒽醌 - 3- O- (3′,6′- O-二乙酰基 ) - α-鼠李糖 12 β- D-葡萄糖苷 ( )、1,3,6 -三羟基 - 2 -甲基蒽醌 - 3-O- (4′,6′- O-二乙酰基 ) -α-鼠李糖 12 β- D-葡萄糖苷 ( )和 1,3,6 -三羟基 - 2 -甲基蒽醌 - 3- O-β- D-葡萄糖苷 ( )。关键词 林茜草 1,3,6 -三羟基 - 2 -甲基蒽醌 - 3- O- (4′,6′- O-二乙酰基 ) - α-鼠李糖 12 β- D-葡萄糖苷 1,3,6 -三羟基- 2 -甲基蒽醌 - 3- O- β-

Eleven compounds were isolated from the ethyl alcohol extract of the root of Rubia sylvatica Nakai On the basis of physicochemical properties and spectral data, these compounds were identified as: 5-hydroxy-naphtho [1,2-b] furan-4-carboxylic acid methyl ester (Ⅰ),rubimaillin (Ⅱ), 1-hydroxy-2-methyl-9, 10-anthraquinone (Ⅲ), β-sitosterol (Ⅳ), daucosterol (Ⅴ), 1, 3, 6-trihydroxy-2-methyl-9, 10-anthraquinone-3-O-(-6′-O-acetyl)-α-rhamnosyl (1→2)-β-D-glucoside (Ⅵ), 1, 3, 6-trihydroxy-2-methyl-9, 10-anthraquinone-3-O-α-rhamnosyl(1→2)-β-D-glucoside (Ⅶ),1,4-dihydroxy-3-prenyl-2-naphtholic acid methyl ester (Ⅷ), 1, 3, 6-trihydroxy-2-methyl-9, 10-anthraquinone-3-O-(3′, 6′-O-diacetyl)-α-rhamnosyl(1→2)-β-D-glucoside (Ⅸ), 1, 3, 6-trihydroxy-2-methyl-9, 10-anthraquinone-3-O-(4′, 6′-O-diacetyl)-α-rhamnosyl (1→2)-β-D-glucoside (Ⅹ), 1, 3, 6-trihydroxy-2-methyl-9, 10-anthraquinone-3-O-β-D-glucoside (Ⅺ)