静脉滴注人血丙种球蛋白治疗喘憋性肺炎136例临床分析

The Analysis of Curative Cffect of Intravenous Immunoglobulin on 136 Eases Asthmatic Suffocating Pneumonia

目的:评估静脉注射丙种球蛋白(IVIG)治疗喘憋性肺炎的临床疗效。方法:将自2007年以来于我科治疗的136例喘憋性肺炎患儿随机分为两组,一组为治疗组,一组为对照组,两组患儿均采用相同的综合性治疗,治疗组在对照组治疗基础上予以每次IVIG 200mg/kg,静脉点滴,1次/d,疗程为3-4d,记录两组患儿症状、体征消失时间及住院天数。结果:治疗组患儿喘憋和肺部体征消失时间明显缩短(P分别<0.01和<0.05),住院天数缩短不显著(P>0.05)。结论:IVIG治疗喘憋性肺炎的临床疗效较确切,方便、安全,可作为佐治喘憋性肺炎的主要药物。

Objective： To evaluate the clinical curative effect of asthmatic suffocating pneumonia by intravenous immunoglobulin { IVIG）. Method： 136 children with sick asthmatic suffocating pneumonia and cured in our department since 2007, They were divided into two groups, one group is therapy group, the oth- er was control group, took the same comprehensive treatment on the sick children in two groups, The therapy group were given IVIG on the base of control group, 200mg/kg once for intravenously daily, the course of treatment was 3-4 days, to record the time of disappearance of symptoms and signs and hospital days of the sick children in the two groups. Result： The time of disappearance of breath holding and pulmonic signs shorten obviously in therapy group （P〈0.01 and P〈0.05 differencely）. Conclusion： The clinical curative effect of asthmatic suffocating pneumonia by intravenous immunoglobulin is relative certain, convenient and safe, It can be used to cure asthmatic suffocating pneumonia as chief drug.