摘要
在前列腺癌根治治疗 方法中引入放射治疗,始于20世纪50年代斯坦福大学的Bagshaw。过去临床30年的实践经验证明,局部控制率可高达65％-88％。 放射治疗失败的主要原因是常现放疗技术未能保证给予肿瘤的根治剂量,因为肿瘤细胞对放射线的抗拒,或根据肿瘤影像做出的治疗计划(TPS)的靶体积错误,肿瘤靶区没有充分的边界。3D CRT解决了前列腺癌对放射线抗拒的问题,而且在提高局部控制率的同时不增加放射线的毒副作用。
The radiother-apy was intro duced to radical cure of prostate cancer by Bagshaw at Stanford University in 1950s. The local control rate was 65% -85% in clinical ex-periences during the last 30 years. The main reason of irradiation failure was that not e-nough radical dose was given to tumor be-cause of the radioresistance of tunor celis, or of the incorrect tumor target volume of TPS based on radiagram, or of not adequate margin of tumor target region.
The radioresistence problem of prostate cancer is solved with 3D CRT. Local control rate is im-proved, while complications of irradiation are not raised with 3D CRT.
出处
《当代医学》
2000年第8期46-50,共5页
Contemporary Medicine
关键词
前列腺癌
放射治疗
外照射
适形放疗
prostate cancer, radiotherapy, external -bean radiation therapy, 3D conformal therapy, interstitial irradiation, postoperative radiotherapy, combination therapy with radiotherapy and endocrinotherapy, new approaches for improving irradiation ef
