摘要
嗜麦芽寡养单胞菌 (Stenotrophomonasmaltophilia,简称Sm)是一个在环境中广泛存在的非发酵革兰阴性菌,容易在患有严重基础性疾病的住院病人中发生感染,病死率较高。Sm对大多数抗菌药物高度耐药,给临床用药带来困难。复方新诺明、多西环素是治疗Sm感染的首选药物,氟喹诺酮类、替卡西林/克拉维酸和复方新诺明联合用药有较好的抗菌活性。
St. maltophilia is a non -fer-mentative, Gram -negative bacillus that is widespread in the environment. Emerging as an important cause of nosocomial infection, it is more commonly isolated from patients with serious underlying diseases. The organ-ism is usually resistant to most antimicrobial agents, which Ieaves few options for thera-py and carries a high mortality. TMP-SMZ or doxycycline may be the good choice for infections caused by St. maltophilia, fluoro -quinolones or the combination of TMP -SMZwith ticarcillin/clavulanic acid showed high activities against St. maltophilia.
出处
《当代医学》
2000年第8期53-56,共4页
Contemporary Medicine
