急性心肌梗死患者急诊cTnI水平与冠脉病变程度相关性研究

Correlation analysis between troponin I level before emergency CAG and the extent of coronary artery lesion in acute myocardial infarction

目的研究急诊cTnI检测对于急性心肌梗死患者病变程度及预后相关性。方法选取该院2011年1月—2011年12月就诊的92例急性心肌梗死并急诊行经皮冠状动脉造影术的患者,根据其手术前急诊检测cTnI水平分组,A组cTnI<0.4ng/mL,B组cTnI≥0.4ng/mL,对2组患者的辅助治疗情况、住院天数进行比较,同时分析cTnI水平与冠脉病变严重程度相关性。结果 cTnI≥0.4ng/mL组患者辅助治疗比例高,住院时间长,两组患者辅助治疗比例、住院天数有明显差别(P值分别为:P=0.042,P=0.029)。术前cTnI水平与冠脉病变评分呈正相关关系(r=0.474,P<0.01)。结论急性心肌梗死患者术前cTnI水平,对预测病变严重程度、辅助治疗情况、住院天数等有较好的临床价值。

Objective To investigate the value of cardiac troponin I （cTnI）level on predicting the extent of coronary artery lesion in patients with acute myocardial infarction. Methods In our hospital from January 2011 to December 2011 for treatment of 92 AMI patients received emergency CAG were enrolled in this study. They were given cTnI test before coronary artery angiography, and were divided according to the level of cTnI into two groups. The patients whose cTnI 〈 0.4pg/mL were in group A, and the whose cTnI~〉0.4ng/ mL were in group B. The number of days in hospital between two groups as well as adjuvant therapies, were compared. The correlation between cTNI and the coronary artery lesion score was analyzed too. Results Higher levels of plasma cTnI were related to more days in hospital, as well as more adjuvant therapies （P=0.042, P=0.029, respectively）.The plasma cTnI levels were positively correlated with the coronary artery lesion score in AMI patients （r=0.474, P 〈 0,001 ）. Conclusion For patients received emergency CAG, cTnI levels tested before PCI can be used as an useful predictor for adjuvant therapies, coronary artery lesion and the number of days in hospital.