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恶性肿瘤中细胞间紧密连接蛋白claudins的研究现状 被引量:1

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摘要 恶性肿瘤的浸润和转移是其最重要的生物学特征,目前普遍认为细胞间的黏附力丧失导致细胞连接的破坏与肿瘤细胞的浸润和转移相关。claudin蛋白是构成细胞膜紧密连接至关重要的成分,其异常表达可以导致上皮细胞及内皮细胞结构破坏和功能受损。本文就近年claudins与恶性肿瘤研究进展作一综述。
作者 杨洋 邬黎青
出处 《实验与检验医学》 CAS 2013年第2期146-148,155,共3页 Experimental and Laboratory Medicine
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