慢性开角型青光眼小梁切除术后眼血流动力学改变

Retrobulbar hemodynamic changes after trabeculectomy.

目的 探讨原发性开角型青光眼 (POAG)小梁切除术后眼血流动力学改变。方法 用彩色多普勒 (CDI)检测POAG小梁切除术前、后及非手术眼的视网膜中央动脉 (CRA)、眼动脉 (OA)的血流动力学改变情况。结果 术后 2周及 3月CRA平均血流速度 (Vmean)和舒张末期血流速度 (Vmin)比术前增加 ,阻力指数 (RI)下降 ,有显著性差异 ;OA在术后 2周及 3月仅Vmean比术前增加 ,RI下降 ,差异有显著性。非手术眼CRA无显著性改变 ,OA第 2次测量RI下降 ,差异有显著性。

Objective To evaluate whether hemodynamic changes occur in the retrobulbar circulation after trabeculectomy.Methods The blood flow of central retinal artery (CRA) and ophthalmic artery(OA) were measured by colour Doppler imaging(CDI) of both eyes before trabeculectomy and after surgery of primary open angle glaucoma(POAG). Results A statistically significant increase was oberserved in the mean and end diastolic velocity and a significant decrease in the vascular resistance of the central retinal artery at approximately two weeks and three months after surgery.The ophthalmic artery was only attained a statistically significant increase for mean velocity in resistance.The nonoperative eyes did not shaw a statistically significant change in CRA and OA. Conclusion Sustained hemodynamic changes occur in retrobulbar circulation after trabeculectomy in patients with POAG.