调胃汤治疗功能性消化不良的临床观察

Clinical Effect of Stomach Regulating Decoction on the Treatment of Functional Dyspepsia Patients

目的:观察调胃汤治疗功能性消化不良的临床疗效。方法:将76例患者随机分为2组。治疗组38例采用调胃汤治疗,对照组38例予以多潘立酮和奥美拉唑胶囊口服治疗。观察2组治疗前后餐后饱胀不适、早饱、上腹痛、上腹烧灼感评分和证候疗效。结果:治疗后治疗组在餐后饱胀不适、早饱、上腹痛、上腹烧灼感4组症状积分较治疗前明显改善(P<0.01);对照组餐后饱胀不适、早饱2组症状积分明显改善(P<0.01);治疗组在上腹烧灼感方面疗效优于对照组(P<0.01);在餐后饱胀不适、上腹痛方面疗效优于对照组(P<0.05)。治疗组总有效率为94.7%,对照组为81.6%,2组比较,差异有显著性意义(P<0.05)。2组治疗期间均未见不良反应,治疗前后肝肾功能、血常规、心电图等检查项目均正常。结论:调胃汤治疗功能性消化不良餐后饱胀不适、早饱、上腹痛、上腹烧灼感效果显著。

Objective: To observe the clinical effect of Stomach Regulating Decoction on the treatment of functional dyspepsia patients.Methods: 76 patients were randomly divided into 2 groups,38 per group.The patients in the treatment group were treated with the decoction while the patients in the control group were given domperidone and omeprazole capsule treatment.The postprandial fullness discomfort,early satiety,epigastric pain and epigastric burning sensation of 2 groups were observed before and after the treatment and their score and syndrome therapeutic effect were evaluated.Results: The symptoms of the postprandial fullness discomfort,early satiety,epigastric pain and epigastric burning sensation of the treatment group in 4 groups significantly improved after the treatment(P < 0.01).The effectiveness of the epigastric burning sensation of the treatment group was better than that of the control group.The symptoms of the postprandial fullness discomfort and early satiety of the 2 groups improved significantly(P < 0.01).The treatment group was better than that of the control group(P < 0.01) in term of epigastric burning sensation curative effect and also better than that of the control group in the postprandial fullness discomfort,upper abdominal pain and side effects(P < 0.05).The total effective rate of the treatment group was 94.7% while that of the control group was 81.6%.The comparison of the 2 groups showed significant difference(P < 0.05).During treatment,there were no adverse reaction in the 2 groups and their blood routine,ECG,liver and kidney function tests were normal before and after the treatment.Conclusion: Stomach Regulating Decoction has an obvious effect on the treatment of functional dyspepsia such as postprandial fullness discomfort,early satiety,epigastric pain and epigastric burning sensation.