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Daxx在细胞凋亡中的研究进展 被引量：1

Progress in the cell apoptosis of Daxx
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摘要 Fas死亡结构域相关蛋白(Fas death domain-associated protein,Daxx)是一种高度保守核蛋白,能与Fas死亡结构域结合,激活Jun氨基端激酶通路促细胞凋亡,在某些情况下Daxx也具有抗凋亡作用。Daxx在细胞凋亡中起着最重要的作用,这将为某些疾病的发病机制研究提供一定的理论与实践基础。 As a highly conserved nuclear protein, Fas death domain-associated protein （Daxx） can activate the Jun-Nterminal kinase （JNK） pathway by binding to Fas death domain. In some cases, Daxx also has anti-apoptosis capacity. Daxx plays a significant role in apoptosis, which may lay a theoretical base for pathogenesis of some diseases.
作者 刘锦红 庹勤慧
机构地区 南华大学药物药理研究所 湖南中医药大学药学院药理教研室
出处 《国际病理科学与临床杂志》 CAS 2013年第2期145-149,共5页 Journal of International Pathology and Clinical Medicine
基金 国家自然科学基金(30971267)~~
关键词 Fas死亡结构域相关蛋白 促凋亡 抗凋亡 Fas death domain-associated protein pro-apoptosis anti-apoptosis
分类号 R363 [医药卫生—病理学]
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国际病理科学与临床杂志
2013年 第2期

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