2011年四川省健康人群钩端螺旋体血清学监测

Serological Surveillance of Leptospirosis Among Healthy Population in Sichuan,2011

目的了解四川省健康人群钩体抗体水平及菌群分布,为制定钩端螺旋体病(钩体病)防控措施提供科学依据。方法对监测点采集的血清用显微凝集试验(MAT),进行15群15型钩体抗体检测。结果 2011年各监测点共采集1111份健康人血清,经检测含10个血清群钩体抗体,钩体的抗体阳性率为21.06%。澳洲群占39.60%、黄疸出血群为37.92%、秋季群7.72%、七日热群7.38%。峨嵋、雅安2个监测点的抗体水平高于全省平均水平。结论全省健康人群钩体抗体阳性率水平较往年低,存在发生局部钩体病流行的条件,应积极做好钩体病的各项防控措施,防止疫情暴发。

Objective To investigate the serogroups, types of leptospirosis antibody titer and the serogroup distri-butions among the healthy population in Sichuan, and to provide the scientific evidence for the disease control and prevention. Methods The MAT tests were employed to measure the fifteen serogroups and fifteen types of leptospirosis antibody of serum samples taken from the healthy people according to national standard. Results At monitoring point, 1 111 healthy human serum were collected in all, containing 10 serotypes. Leptospira anti-body positive rate was 21.06%, and the proportion for each subtypes were L. Aust （ 39.60% ）, L. Icte （37.92%）, L. Autu （7.72%）, L. Hebd （7.38%） respectively. The antibody levels of the the Ya＇an and Emei city were much higher than the provincial average level in the same year. Conclusion The province＇s over-all level of antibody positive rate was lower than the previous years, and the antibody titers was comparatively low too. There are basic conditions for local leptospirosis prevalence, timely control measures should be taken to prevent the outbreak.