一种双功能的含呋喃和异噁唑环酰腙Cu(Ⅱ)配合物的合成及其性能研究

Synthesis and study on a difunctional copper(Ⅱ) complex for acylhydrazone with isoxazole and furan heterocycles

合成了一种含异噁唑环和呋喃环的新型酰腙的Cu(Ⅱ)配合物,通过红外、紫外光谱和荧光光谱等研究了该配合物的结构及其性质,同时测定了铜配合物对枯草芽孢杆菌、绿脓杆菌、大肠杆菌和金黄色葡萄球菌的抑菌活性。结果表明,铜配合物的水溶液在484 nm处呈现一强蓝色荧光发射峰。铜配合物有较好的抑菌效果,其抑菌活性明显优于配体。该配合物兼有荧光性能和抑菌活性,可应用在材料科学、光动力学疗法等领域。

A novel copper complex for acylhydrazone with isoxazole and furan heterocycles was synthesized and thoroughly investigated by IR, UV and fluorescence spectroscopy. Furthermore, the results of antibacterial activities indicate the compound has broad-spectrum against Bacillus subtili, pseudomonas aeruginosa,Escherichia coli and Staphylococcus aureus. The results show that the title compound gives rise to strong blue fluorescence with a peak at 484 nm. Therefore, the complex exhibits both antibacterial activity and photoluminescent property, namely, difunctionality, suggesting that it has potential applications in many fields such as material science and photodynamic therapy.