样品前处理与色谱在线分析技术研究进展

Progresses on On-line Coupling Method of Sample Pretreatment with Chromatography Analysis

色谱技术是目前应用最为广泛的分离分析技术,而传统色谱分析方法中样品采集、样品前处理、色谱分析3个步骤各自独立,使分析过程耗时、耗力、耗试剂,容易造成目标物损失而产生误差。色谱在线分析技术是在线实现样品的前处理及分析过程,可有效解决上述不足,已成为分析化学的前沿课题。该文讨论了在线色谱分析方法的设计及相关联用技术,综述了在线色谱分析技术的最新进展。

Chromatography is widely-used analysis technique today.However,in the traditional off-line chromatographic analysis procedures,the sampling,sample pretreatment and chromatographic analysis are conducted independently.These off-line procedures are solvent-wasted,time and labor consumed,easy to produce error and lead to low recovery.On-line coupling method could tackle the above problems,and has become the front project in the field of analytical chemistry.The design consideration of the on-line coupling techniques in the chromatographic analysis was discussed in this review.Furthermore,the related techniques and the latest progresses in this field were summarized.