摘要
目的:观察安糖1号治疗脾肾气阴两虚型初发2型糖尿病并代谢综合征的临床疗效。方法:将中医辨证为脾肾气阴两虚型初发2型糖尿病并代谢综合征患者80例随机分为2组各40例。对照组予合理饮食,运动治疗,戒烟限酒,调畅情志等糖尿病健康教育;治疗组在对照组基础上给予自拟安糖1号加减治疗。观察2组血糖、糖化血红蛋白、胰岛素、血脂、体重指数、血压及中医证候积分变化情况。结果:3个月后2组糖代谢各指标均较前改善,差异均有显著性意义(P<0.05);组间比较差异有统计学意义(P<0.05)。治疗组空腹血胰岛素(FINS)、2小时胰岛素(2HINS)均较前改善,差异均有统计学意义(P<0.05)。治疗组FINS、2hINS、总胆固醇(TC)、甘油三酯(TG)、体重指数(BMI)、血压(BP)与对照组比较,差异有统计学意义(P<0.05)。2组中医证候积分均较前明显下降,差异有统计学意义(P<0.01),且治疗组改善优于对照组(P<0.05)。停服中药1月后,治疗组空腹血糖(FBG)、餐后2小时血糖(P2hBG)、血压(BP)均低于对照组,差异有统计学意义(P<0.05)。结论:安糖1号治疗脾肾气阴两虚型初发2型糖尿病并代谢综合征有显著疗效。
Objective: To observe clinical effects of AnTangNo.1 in treating diabetes mellitus type two of dnal deficiency pattern of spleen-kidney Qi-Yin at primary stage complicated with metabolism syndrome. Method: Eighty patients were differentiated as dual deficiency pattern of spleen-kidney Qi-Yin and divided into two groups. The control group received diabetes education including regular diet, exercises, quitting smoking and less alcohol, keeping good moods and others. The treatment group took self-made modified AnTang No.1. Changes of blood glucose, glycosylated hemoglobin, insulin, blood lipid, body mass index and TCM syndrome integral of both groups were observed. Result: The indexes of glycometabolism in both groups after three months were all improved and the difference showed statistical meaning(P〈0.05);Fasting insulin and 2 h insulin of the treatment group were improved and the difference was significant (P〈0.05). Comparisons in fasting insulin, 2 h insulin, total cholesterol (TC), triglyceride (TG), body mass indexes (BMI) and blood pressure between both groups showed the difference and it had significant meaning (P〈0.05). TCM syndrome integral of both groups were lowered significantly and the differences were significant (P〈0.01), the improvements of the treatment group were superior to the control group (P〈0.05). After stopping the herbs for one month, fasting blood glucose (FBG), 2 h postprandial blood glucose and blood pressure of the treatment group were lower than that of the control group and the differences were remarkable (P〈0.05). Conclusion: AnTang No.1 presents remarkable effects in treating diabetes mellitus type two of dual deficiency pattern of spleen-kidney Qi-Yin at primary stage complicated with metabolism syndrome.
出处
《西部中医药》
2013年第5期1-4,共4页
Western Journal of Traditional Chinese Medicine
关键词
糖尿病
2型
初发
代谢综合征
脾肾气阴两虚型
安糖1号
diabetes mellitus
type two, at primary stage
metabolism syndrome
dual deficiency pattern ofspleen-kidney Qi- Y in
A n Tong No. 1