产后抑郁与认知功能损害的相关性分析

The Relativity between Postpartum Depression and Cognitive Impairment

目的:探讨产后抑郁与认知功能损害的相关性。方法:对2008年10月至2012年2月住院的450例产妇进行产后抑郁、一般情况与认知功能调查。结果:产妇发生产后抑郁者100例,发生率为22.2%;教育程度、意外妊娠、妊娠合并疾病、初产妇与分娩方式为影响产后抑郁的主要危险因素(P<0.05);抑郁组完成分类数、正确应答数低于对照组(P<0.05),抑郁组完成总应答数、总错误数、完成一个分类卡片数高于对照组(P<0.05);抑郁状况与完成分类数和正确应答数呈负相关,与完成总应答数和总错误数呈正相关。结论:产后抑郁症的发生是多因素影响的结果,多伴随有认知功能损害,并与认知功能损害存在相关关系。

Objective： To explore the relativity between postpartum depression and cognitive impairment. Method： All 450 cases of delivery women admitted from October, 2008 to February, 2012 were selected and the conditions of postpartum depression, general information and cognitive function were investigated. Result： There were 100 cases suffering from postpartum depression and the incidence was 22.2%; educational background, acci- dental pregnancies, pregnancy complicated with other diseases, primipara and the way of labor were the major risk factors for postpartum depression （P〈0.05）; the number of completed categories and correct responses of the de- pression group were lower than that of the control group （P〈0.05）, the total number of completed responses, total wrong number and the number of completed cards of the depression group were higher than that of the control group （P〈0.05）; the condition of depression was negatively related to the number of completed categories and right re- sponses, positively related to the number of completed responses and total wrong number. Conclusion： The inci- dence of postpartum depression is the result of multiple factors, usually accompanied with and related to cognitive impairment.