急性肠系膜上动脉栓塞患者血清甲状腺激素及TSH水平的观察

The Observation of Serum Thyroid Hormone and TSH in Patients with Acute Superior Mensenteric Thrombosis

目的:探讨急性肠系膜上动脉栓塞患者血清甲状腺激素和TSH水平以及手术治疗后血清甲状腺激素及TSH水平的变化规律。方法:收集28例急性肠系膜上动脉栓塞患者,均接受肠系膜上动脉切开取栓手术治疗,分别于手术前、后1d、3d、7d、14d抽取空腹静脉血,采用放射免疫分析检测血清FT3、FT4、T3、T4及TSH水平;同时选择同龄同性别体检健康人员作为正常对照组,以同样方法检测。结果:28例急性肠系膜上动脉栓塞患者血清FT3、FT4、T3、T4均明显低于正常对照组,且以危重患者最明显;手术后血清甲状腺激素进一步降低,手术后3d降至最低水平,手术后7d逐渐回升,术后14d恢复手术前水平。结论:急性肠系膜上动脉栓塞患者存在低甲状腺激素血症,且以危重患者最明显,手术创伤后进一步加重这种现象,术后血清甲状腺激素随病情恢复逐渐恢复至术前水平;围手术期检测血清甲状腺激素及TSH水平有助于了解病情轻、重及手术后病情恢复情况。

Objective To investigate the alterative regularity of serum thyroid hormone and TSH periopertion in patients with acute superior mensenterie thrombosis. Methods The 28 patients and 28 normal eontrels with sams age and gender were selected and examined their serum thyroid hormone and TSH simueltaneously. The serum levels of thyroid hormone （ ineludiag FT3, FT4, T3, T4 ） and TSH were determined by radioimmunoassay at perioperation （just before emboleetomy and the days of the first, third, 7^th and 14^th postoperation） in the 28 patients received emboleetomy. Rosults The lower levels of thyroid hormone were found in the 28 patients with acute superior mensenterie thrombosis, especially in the severe ones; meanwhile the lower levels of thyroid hormone of 28 operated patients were deduced further in the first day and the third day after operation since then returned gradually to the primary levels on the 14 days. Conclusion The patients have lower levels of thyroid hormone especially in the severe ones, which are aggravated postoperation and which will be corrected on the 14 day postoperation. It is helpful to realize the degrees of severity and to judge the perioperative convalescence situation in the patients received embolectomy.