新生儿疼痛的干预方法和止痛措施的临床效果研究

Research on Effects of Intervention and Analgesic Methods on Neonate Pain

目的探讨几种常用非药物干预方法及联合干预在临床上减轻新生儿操作性疼痛的效果.方法在足跟采血后1min、5min、10min分别采用新生儿疼痛量表（NIPS）评估疼痛程度.将120例住院新生儿随机分为4组,每组30例.其中对照组在全过程不给予任何缓解疼痛的干预措施.干预组Ⅰ采用体位支持、干预组Ⅱ采用口服25%葡萄糖溶液＋非营养性吸吮（NNS）的干预方案、干预组Ⅲ采用体位支持＋口服25%葡萄糖溶液＋NNS的联合干预方案.结果与对照组比较,干预组Ⅰ的NIPS评分差异无统计学意义（P〉0.05）,但干预组Ⅱ、干预组Ⅲ NIPS评分差异有统计学意义（P〈0.05）;与刺激后1min比较,刺激后5min及刺激后10min各组的NIPS评分均迅速下降.结论体位支持无明确镇痛效果,联合干预方法Ⅱ、Ⅲ均有明确镇痛作用,其中联合干预方案Ⅲ的效果最好.

Objective To explore effects of non-pharmacological and joint interventions on neonate operating pain.Methods To assess 1min,5min,10min level of pains according to the NIPS（neonatal infant pain scale） after neonatal blood collection in heel,120 hospitalized neonates were randomly divided into 4 groups.The control group never received any interventions to relieve the pains throughout.Intervention group Ⅰused body posture support,group Ⅱ used 25% glucose solution ＋ non-nutritive sucking（NNS）,group Ⅲ used body posture support ＋25% glucose solution ＋ NNS.Results There＇s no statistical difference between the control group and intervention group Ⅰ（P〉0.05）,while there is difference between intervention group Ⅱ and Ⅲ（P〈0.05）;NIPS scores decrease rapidly on 5min and 10min post-stimuli compared with 1min.Conclusions Body posture support provides no significant analgesia effect,joint interventionsⅡand Ⅲ have significant analgesic action,which intervention Ⅲ is better.