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不同性别老年冠心病冠状动脉旁路移植术患者代谢性危险因素特征 被引量:9

Characteristics of metabolic risk factors in elderly coronary heart disease patients after coronary artery bypass grafting
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摘要 目的探讨不同性别行冠状动脉旁路移植术(CABG)治疗的老年冠心病患者代谢性危险因素特征。方法选择老年冠心病CABG患者398例,分为男性组272例,女性组126例,比较2组患者的代谢性危险因素特征。结果女性组体重指数、收缩压、TC、HDL-C、LDL-C和TG均高于男性组(P=0.003,P=0.000),血尿酸水平低于男性组,差异有统计学意义(P=0.000)。2组的年龄、舒张压、空腹血糖、糖化血红蛋白水平比较,差异无统计学意义(P>0.05)。女性组血脂异常的比例高于男性组,吸烟的比例低于男性组(P=0.000),2组高血压、糖尿病和多支血管病变的比例比较,差异无统计学意义(P>0.05)。结论老年女性冠心病CABG患者的血脂异常和收缩压升高更为严重,吸烟比例和血尿酸水平低。 Objective To study the characteristics of metabolic risk factors in elderly coronary heart disease (CHD) patients after coronary artery bypass grafting (CABG). Methods Three hundred and ninety-eight elderly CHD patients were divided in male patients group (n=272) and female patients group (n= 126). The characteristics of metabolic risk factors in the two groups were compared. Results The BMI,SBP,and serum TC, HDL-C, LDL-C and TG levels were sig- nificantly higher whereas the serum UA level was significantly lower in female patients group than in male patients group (P = 0. 003, P= 0. 000). No significant difference was found in age, DBP,and fasting blood glucose and HbAlc levels between the two groups (P〉0.05). The per- centage of dyslipidemia was higher whereas that of smoking was lower in female patients group than in male patients group (P=0. 000). No significant difference was observed in the incidence of diabetes mellitus, hypertension and multiple vessel lesion between the two groups (P〉0.05). Conclusion The percentage of dyslipidemia and elevated SBP is significantly higher whereas that of smoking and serum UA level is significantly lower in elderly female CHD patients than in eld- erly male CHD patients after CABG.
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2013年第6期569-571,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词 冠心病 冠状动脉旁路移植术 非体外循环 代谢疾病 血脂异常 糖尿病 性别因素 危险因素 coronary disease coronary artery bypass, off-pump metabolic diseases dyslipidemias diabetes mellitus ~ sex factors risk factors
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参考文献9

  • 1Flather M,Rhee JW,Boothroyd DB,et al. The effect of age on outcomes of coronary artery bypass surgery compared with balloon angioplasty or bare metal stent implantation among pa- tients with muhivessel coronary disease. A collaborative analy- sis of individual patient data from 10 randomized trials. J Am Coll Cardiol,2012,60 : 2150-2157.
  • 2Saxena A,Dinh D, Smith J A,et al. Sex differences in outcomes following isolated coronary artery bypass graft surgery in Aus-- trallan patients:analysis of the Australasian Society o{ Cardiac and Thoracic Surgeons cardiac surgery database. Eur J Cardio- thorac Surg,2012,41:755 762.
  • 3Newton KM. Risk factors for coronary heart disease in worn en. Nuts Clin North Am, 2004,39 : 145-163.
  • 4周俊,周京敏,金雪娟,虞勇,崔晓通,付明强,葛均波.上海心脏健康研究队列中40~70岁女性年龄、绝经年限与心血管病危险因素聚集关系探讨[J].内科理论与实践,2012,7(5):348-351. 被引量:5
  • 5Okada K, Ueda Y, Takayama T, et al. Influence of achieved low density lipoprotein cholesterol level with atorvastatin ther apy on stabilization of coronary plaques sub-analysis of the TWINS study. Circ J, 2012,76 : 1197-1202.
  • 6Prugger C, Keil U, Wellmann J, et al. Blood pressure control and knowledge of target blood pressure in coronary patients across Europe: results from the EUROASPIRE l]I survey. J Hypertens, 2011,29 : 1641 1648.
  • 7Frey P,Waters DD, DeMicco DA, eta[. Impact of smoking on cardiovascular events in patients with coronary disease receiv ing contemporary medical therapy [from the treating to new targets (TNT) and the incremental decrease in end points through aggressive lipid lowering (IDEAL) trials]. Am J Car diol, 2011,107:145-150.
  • 8李曦,李艳芳.不同年龄冠心病患者血尿酸水平变化特点的临床分析[J].中华老年心脑血管病杂志,2010,12(7):614-616. 被引量:22
  • 9Holman RR,Paul SK, Bethel MA, et al. 10-year follow-up o{ intensive glucose control in type 2 diabetes. N Engl J Med, 2008,3591577-]589.

二级参考文献18

  • 1马士新,魏盟,张昀昀,李京波,刘蓉,陈齐虹.血尿酸不是冠心病的独立危险因素[J].中国实用内科杂志:临床前沿版,2006,26(1):151-152. 被引量:10
  • 2中国成人血脂异常防治指南[J].中华心血管病杂志,2007,35(5):390-419. 被引量:5224
  • 3Brodov Y, Chouraqui P, Goldenberg I, et al. Serum uric acid for risk stratification of patients with coronary artery disease. Cardiology, 2009,114 : 300-305.
  • 4Rathmann W, Haastert B, Icks A, et al. Ten-year change in serum uric acid and its relation to changes in other metabolic risk factors in young black and white adults: the CARDIA study. Eur J Epidemiol, 2007,22 :439-445.
  • 5Athyros VG, Elisaf M, Papageorgiou AA, et al. Pathogenesis and treatment of kidney disease and hypertension--Effect of statins versus untreated dyslipidemia on serum uric acid levels in patients with coronary heart disease: a subgroup analysis of the GREek Atorvastatin and Coronary-heart-disease Evaluation(GREACE) study. Am J Kidney Dis,2004,43:589-599.
  • 6Okura T, Higaki J, Kurata M, et al. Elevated serum uric acid is an independent predictor for cardiovascular events in patients with severe coronary artery stenosis: subanalysis of the Japanese Coronary Artery Disease(JCAD) Study. Cire J, 2009,73: 885-891.
  • 7Ruggiero C, Cherubini A, Ble A, et al. Uric acid and inflammatory markers. Eur Heart J,2006,27: 1174-1181.
  • 8丰有吉,沈铿.妇产科学[M].北京:人民卫生出版社,2010,7(2):60.
  • 9中华人民共和国卫生部疾病控制司.中国成人超重和肥胖症预防控制指南[M],北京:人民卫生出版社,2006,1-20.
  • 10Zhang XH, Lu ZL, Liu L. Coronary heart disease in China[J]. Heart, 2008, 94(9): 1126-1131.

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