鲁北地区子宫内膜癌306例临床病理分析

Clinicopathological analysis of 306 cases with endometrioid cancer in northern Shandong area

目的 研究子宫内膜癌的病理类型及临床特点。方法 对鲁北地区306例子宫内膜癌患者的临床病理资料进行回顾性分析。结果 子宫内膜癌主要包括两种病理类型：子宫内膜样腺癌和非子宫内膜样腺癌,子宫内膜样腺癌占内膜癌总数的90%,非子宫内膜样腺癌占总数的10%。非子宫内膜样腺癌与子宫内膜样腺癌相比,发病年龄较大［（59.32±7.77）岁］,在绝经后患者的构成比较高（90%）,病理分期较晚（P=0.000）,组织学分级高（P=0.000）,易发生深肌层浸润（P=0.014）,易发生淋巴转移（P=0.006）,术后复发率高（P=0.000）。结论 非子宫内膜样腺癌与子宫内膜样腺癌在临床病理方面存在显著差异,恶性程度高,预后差,需要重视。

Objective To explore the clinicopathology characteristics of endometrial adenocarcinoma and non-endometrial adenocarcinoma.Methods The clinical data of 306 patients with endometrioid cancer were analyzed retrospectively.Results The patients with endometrial adenocarcinoma accounted for 90% of all patients,and the patients with non-endometrial adenocarcinoma accounted for 10%.Compared with the patients with endometrial adenocarcinoma,the average age of the patients with non-endometrial adenocarcinoma was older[（59.32±7.77）years],the constitution ratio of postmenopausal patients was higher（90%）,the clinicopathologic stage was later（P=0.000）,the grade of histology was higher（P=0.000）,the myometrial invasion was deeper（P=0.014）.The patients with non-endometrial adenocarcinoma were prone to occur lymph metastasis（P=0.006）,and the recurrence rate was higher（P=0.000）.Conclusion There is significant defference between endometrial adenocarcinoma and non-endometrial adenocarcinoma,the patients with non-endometrial adenocarcinoma has poor pronosis,and we should pay more attention to it.