冠心病血浆HDL-C,APOAI,APOB和LP(a)相关性探讨

The investigation of the interrelation among HDL-C, APOAI, APOB and LP(a) in CHD

笔者测量了冠心病患者和对照组血液中的脂类及载脂蛋白的含量 ,发现当高密度脂蛋白胆固醇 ( HDL-C) <0 .9mm ol/L、载脂蛋白 AI( A POAI) <1.0 g/L、载脂蛋白 B( APOB) >0 .9g/L 及脂蛋白〔LP( a)〕>2 0 0 m g/L,患者的发病率明显高于对照组 ( P<0 .0 1)。对于 CHD的这四个危险因素 ,在临床上可用于对一般人群 CH D的调查及预防治疗后的观察 ,都有非常重要的意义。

The authors measured the lipid and apo lipoprotein in the blood of the coronary heart disease (CHD) group and the control group. The incidence of CHD is significantly higher in the CHD group than control group (P<0.01), when high density lipoprotein cholesterol (HDL C) <0.9mmol/L, apo lipoproteinA Ⅰ(APOAⅠ)<1.0g/L, apo lipoproteinB(APOB)>0.9g/L and lipoprotein(LP(a))>200mg/L. Above mentioned four risk factors can be used to the investigation of the CHD pts of general population and to the observation after prevent treatment of the CHD, and all of them have very important signification.