成人慢性鼻窦炎脓液普通细菌培养及药敏结果分析

Common bacterial culture of adult chronic sinusitis pus and drug sensitivity analysis

目的:总结和分析成人慢性鼻窦炎脓液普通细菌培养及药敏结果,为临床提供用药参考。方法:对来自于本院耳鼻喉科258例患者上颌窦内采集的标本进行培养和药敏试验,并对结果进行分析和总结。结果:258例标本检出阳性157例,共159株致病菌,阳性率为60.85%(157/258);致病菌主要为金黄色葡萄球菌、表皮葡萄球菌、铜绿假单胞菌和真菌。敏感性较高的抗生素为头孢噻肟、左氧氟沙星、哌拉西林/他唑巴坦、亚胺培南以及头孢哌酮。结论:引起成人慢性鼻窦炎的致病菌主要为金黄色葡萄球菌、表皮葡萄球菌、铜绿假单胞菌和真菌;治疗药物应以头孢噻肟、左氧氟沙星、哌拉西林/他唑巴坦、亚胺培南以及头孢哌酮为主要治疗性抗生素。

Objective. To sumerize and analyze the results of common bacterial culture of adult chron- ic sinusitis pus and drug sensitivity so as to provide rational drug use reference for doctors. Meth- ods： Specimens of maxillary sinus collected from 258 patients were cultured and performed drug sensitivi mens, 1 60. 85 tests, and the results were analyzed and summed up. Results： Of the 258 cases of speci- were detected positive with 159 strains of pathogenic bacteria （the total positive rate was the pathogenic bacteria were mainly staphylococcus aureus, staphylococcus epidermidis, pseudomonas aeruginosa and fungus. The higher sensitive antibiotics were cefotaxime, levofloxa- cin, piperacillin/tazobactam, imipenem and cefoperazone. Conclusion. The chief pathogenic bacte- ria tc cause adult chronic sinusitis are staphylococcus aureus, staphylococcus epidermidis, pseudo- monas aeruginosa and fungus, and cefotaxime, levofloxacin, piperacillin/tazobactam, imipenem and cefoperazone are the main effective antibiotics to treat the disease.