老年人尿钙氟锰镁和羟脯氨酸与骨密度的关系

Relationships between urinary calcium, fluorine, manganese, magnesium, hydroxyproline and bone mineral density in aged

目的 探讨影响老年人骨密度的因素及防治老年骨质疏松的措施。方法 采用整群抽样方法对两所高等院校 2 86例 5 0岁以上老人进行骨密度及尿钙、氟、锰、镁 ,羟脯氨酸调查研究。结果 本研究表明女性骨矿物质含量和骨矿物质密度显著低于男性 (P <0 .0 1) ,女性尿钙含量明显高于男性 (P <0 .0 5 ) ,女性尿羟脯氨酸含量明显低于男性 (P <0 .0 1) ,而尿氟含量差别不明显。尿钙、锰、羟脯氨酸与骨矿物含量和骨密度呈现显著性负相关 ,尿氟与尺骨骨矿物含量和骨密度呈现显著性正相关 (P <0 .0 5或P <0 .0 1)。结论 提示尿钙、氟、锰、羟脯氨酸均可影响骨代谢。

Objective To research for the factors influencing the bone mineral density and the measures to prevent and treat the osteoporosis in elderly.Methods With the measure of cluster sampling to study the bone mineral density and urinary calcium, fluorine, manganese, magnesium and hydroxyproline (HOP).Results The bone mineral content (BMC) and bone mineral density(BMD) of female was lower than that of male(P<0.01).The urinary calcium was significantly higher in female than that in male(P<0.05),but the urinary HOP was lower in female than that in male (P<0.01). The urinary fluorine was no significantly difference . It was showed the significantly negative correlation between urinary calcium,munganese,HOP and BMD, and positive correlation between urinary fluorine and BMD and BMC(P<0.05 and P<0.01). Conclusion The urinary calcium, manganese, HOP fluorine may be the factors influencing the bone mineral density of old people.