不同年龄段肾细胞癌患者临床病理特点分析

Clinicopathological features of renal cancer in different ages

目的探讨不同年龄段肾癌患者的临床病理特点。方法分析北京协和医院2002—2012年收治的2 268例肾癌患者的临床病理资料,根据年龄及病理类型分为不同的组别进行分析。结果 2 268例肾癌病例中<40岁,40～59岁和60岁以上患者数目分别为260(11.5%),1 178(51.9%)和830(36.6%)。不同年龄组间患者肿瘤大小及TNM分期无差异。但是,在有临床表现的病例中,<40岁患者组中的症状性肾癌发生率较高;不同年龄组间肾癌的病理学类型无显著性差异。此外,比较年轻患者多采用肾部分切除术,年龄较高患者多采用肾癌根治术。结论应重视对青年人群的健康体检,肾癌治疗的主要方式仍是根治性手术,但应重视保留肾单位手术。

Objective To investigate the clinical pathological characteristics of different age group of patients with renal malignant tumor. Methods We analyzed the clinical and pathological data of 2 268 patients with renal ma lignant tumor admitted in PUMC hospital from 2002 to 2012. Patients were grouped according to age and pathologi cal type. Results Among the 2 268 RCC patients, there was 260（ 11.5% ） ,1178（51.9% ） ,and 830（36.6% ） patients aged 〈40, 40 -59 and over 60 years old respectively. There was no significant differences in tumor size, and TNM stage by age group. However, patients under 40 were significantly more likely to present with symptomat ic tumors. There was no significant differences in histology by age; The surgical treatment of kidney cancer patients of different age groups was in different ways and the percentage of patients treated with partial nephrectomy declined with age. Conclusions The health examination of the youth crowd should be strengthened, the main form of treat ment for kidney cancer is radical surgery, but we also should pay attention to nephron sparing surgery.