结直肠癌美国癌症联合会TNM分期第5、6版与第7版的差异及预后分析和比较

Comparative Analysis of Colorectal Cancer TNM Staging of American Joint Committee on Cancer 5th ed.,6th ed.and 7th ed.

目的比较结直肠癌AJCC分期第5、6版和第7版对患者生存时间预后评估的差异,评价新的结直肠癌美国癌症联合会TNM分期标准的临床应用价值。方法回顾性分析1995-2007年在天津市人民医院接受治疗并具有完整临床病理资料的3 671例患者,以三版分期标准比较其预后情况。结果结直肠癌第7版AJCC分期在T、N、M分期方面均进行了调整,与第5、6版相比,分期标准更为精细化,可以更好地对不同临床结果的患者进行区分。结论与第5、6版相比,第7版分期标准更为合理,精确,但其具体临床价值仍有待进一步探索。

Objective To evaluate clinical value of the 7th ed. colorectal cancer staging AJCC by comparing with the 5th ed. and 6th ed.Methods A retrospective analysis of 3671 colorectal cancer patients with complete clinical data from 1995 to 2007 was performed. The prognostic differences among the 7th ed. colorectal cancer staging AJCC and the 5th ed. and the 6th ed. were analyzed by the Kaplan-Meier method and compared by the Log rank test.Results The 7th ed. showed better performance in prognosis of colorectal cancer patients which adjusted in T, N and M staging. Conclusion 7th ed. show better performance than 5th ed. and 6th ed. , and the further study still be carried out to verify.