EGFR抑制剂调节DNA双链断裂修复对放射敏感度影响的研究进展
摘要
0引言
肿瘤放射治疗过程中DNA损伤具有多样性，包括碱基和核苷酸水平的损伤以及DNA链断裂等。其中DNA双链断裂（double-strand breaks，DSBs）是最常见的损伤，DSBs的修复是一个很复杂的过程，通过以下两条途径进行修复：非同源末端连接（nonhomologous end-joining，NHEJ）和同源重组修复（homologous recombination，HR）。
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2013年第5期502-504,共3页
Cancer Research on Prevention and Treatment
基金
南京军区医药卫生科研资助项目(10MA098)
参考文献31
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