超声造影对肝脏局灶性病变的诊断价值

Diagnostic value of contrast-enhanced ultrasound in focal hepatic lesions

目的观察肝脏局灶性病变的超声造影表现,评价超声造影在肝脏局灶性病变定性诊断中的价值。方法超声造影检查45例肝脏局灶性病变患者,采用编码相位反转技术和时间-强度曲线分析软件,分析肝脏局灶性病灶良恶性鉴别诊断的定量参数变化特征。结果超声造影肝脏恶性病灶始增时间和达峰时间均早于良性病灶及周围肝组织(P<0.05),增强时间短于良性病灶(P<0.01)。良恶性病灶和良性病灶的增强幅度差异无统计学意义,但均高于病灶周围肝组织(P<0.01)。结论应用时间-强度曲线取得的超声造影定量参数变化特征对肝局灶性病变的良恶性鉴别具有重要价值。

Objective To observe the contrast-enhanced ultrasound （CEUS） characteristics of focal hepatic lesions （FHL）, and to assess the value of CEUS in qualitative diagnosis of FHL. Methods CEUS was performed on 45 patients with FHL. Coded phase inversion mode （CPI） was applied during the CEUS examination, time-intensity curve （TIC） was applied to analyze the variational characteristics of quantitative parameters in benign and malignant lesions. Results Arrival time and peak time of malignant lesion group were significantly earlier than those of benign lesion group and surrounding liver tissue （P 〈 0.05）. Enhanced time of malignant lesions was significantly shorter than the benign lesions （P 〈 0.01 ）. Enhance amplitude between the malignant group and benign group had no significant difference ,but it was significantly higher than the surrounding liver tissue （P 〈 0.01 ）. Conclusion The variational characteristics of quantitative parameters obtained from TIC in CEUS have important value in discriminating benign and malignant focal hepatic lesions.