血红素加氧酶-1可能的视网膜视神经保护作用
摘要
血红素加氧酶(HO)是血红素代谢途径中的限速酶,在体内分布广泛。该代谢不仅清除机体内细胞毒性的血红素,其伴随产物一氧化碳、胆绿素、铁/铁蛋白均在机体发挥重要的抗氧化、抗凋亡、抗炎症等效应,因此HO系统作为机体重要的防御系统被人们认识。视网膜组织中HO含量丰富,可以减轻视网膜组织对光刺激、缺血缺氧、氧化应激等危险因素的损伤,本文主要探讨HO-1可能的视网膜视神经的保护作用。
出处
《中国眼耳鼻喉科杂志》
2013年第3期196-198,共3页
Chinese Journal of Ophthalmology and Otorhinolaryngology
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