64层CT在肺动脉高压诊断中的价值

Value of 64-slice spiral CT in the diagnosis of pulmonary arterial hypertension

目的探讨64层CT在肺动脉高压(pulmonary arterial hypertension,PAH)诊断中的价值。方法回顾性分析40例经彩色多普勒超声心动图检查确诊为PAH的患者及42例肺动脉压力正常者的临床及CT资料,测量主肺动脉直径、主肺动脉与升主动脉直径比值、主肺动脉与降主动脉直径比值,并进行统计学分析。结果 PAH组和对照组主肺动脉直径分别为(3.39±0.48)cm、(2.55±0.28)cm;主肺动脉/升主动脉直径比分别为(1.13±0.12)、(0.80±0.14);主肺动脉/降主动脉直径比分别为(1.37±0.24)、(0.98±0.11)。两者差异具有显著的统计学意义(P<0.05)。主肺动脉直径≥2.9cm诊断PAH的敏感性、特异性分别为89%、91%。64层CT诊断PAH的准确性为90.3%。结论 64层CT可明确诊断PAH,并为病因诊断提供更多信息。

Objective To study the value of 64-slice spiral CT in the diagnosis of pulmonary hypertension （PAH）. Methods The clinical data and 64-slice spiral CT data of 40 patients with PAH confirmed by Doppler echocardiography were retrospectively analyzed. 42 persons without PAH were collected as the control group. The main pulmonary artery diameter （MPAD）, the ratio of the main pulmonary artery to ascending aorta （rPA） and the ratio of the main pulmonary artery to descending aorta （rPD） were lined and analyzed respectively. Results The MPAD was （3.39±0.48） cm in patients with PAH and （2.55±0.28） cm in control group on CT images. The rPA was （1.13±0.12） in patients with PAH and （0.80±0.14） in control group. The rPD was （1. 37±0. 24） in patients with PAH and （0. 98±0. 11） in control group. All of the differences were statistically significant （ P〈0.05）. MPAD≥2.9 cm being taken as the criterion, the sensitivity and the specificity for predicting PAH were 89% and 91 % respectively. The accuracy of the diagnosis of PAH by 64-slice spiral CT was 90.3%. Conclusion PAH can be accurately diagnosed by 64-slice spiral CT , which can provide more information for the etiological diagnosis.