阿托品在颈动脉支架置入术中的预防性应用

Preventive Application of Atropine to Patients Receiving Carotid Arteries Stenting

目的:观察阿托品对颈动脉支架置入术(CAS)的颈动脉窦反应的预防作用。方法:行CAS治疗的患者60例,随机分为对照组和阿托品组各30例,阿托品组常规预扩前静脉注射阿托品1 mg,对照组预扩前注射等量生理盐水。观察2组病例球囊扩张及支架植入过程与术后的颈动脉窦反应情况。结果:阿托品组颈动脉窦反应3例(10.0%),对照组颈动脉窦反应11例(36.7%),差异有统计学意义(χ2=5.963,P=0.015)。结论:在CAS中预防性应用阿托品可减少颈动脉窦反应发生率。

Objective： To observe the preventive efficacy of atropine on the carotid sinus syndrome in patients receiving carotid arteries stenting（CAS）. Methods： Sixty patients receiving CAS were randomly divided into atropine group （n=30） and control group （n=30）. The atropine group was given atropine through intravenous injection （1 mg） before the operation, while the control group was given the equal volume of normal saline in the same way. The frequency of the carotid sinus syndrome was detected in both the groups during the operation. Results： There were 3 patients （10.0%） suffering the carotid sinus syndrome in the atropine group while 11 patients with carotid sinus syndrome in the control group （36.7%）. The difference was significant （X^2=5.963,P=0.015）. Conclusion： Atropine may reduce the frequency of the carotid sinus syndrome in patients receiving carotid arteries stents angioplasty.