等离子射频消融对变应性鼻炎患者鼻黏膜激发试验的影响

The effect of plasma radiofrequency ablation on nasal mucosa provocative tests for allergic rhinitis

目的:探讨等离子射频消融对变应性鼻炎(AR)患者鼻黏膜激发试验的影响,以评价手术的疗效。方法:应用等离子射频消融对80例AR患者进行治疗,手术前后测定鼻黏膜激发试验和鼻气道阻力及患者的主观鼻通气感觉,以评价手术对患者的主客观感觉的影响及其两者的相关性。结果:螨虫过敏的AR患者,术前鼻黏膜激发试验呈阳性,术后3个月有72例患者转为阴性,余8例仍为阳性,鼻气道阻力术前为(0.772±0.224)kPa.s/L,术后为(0.221±0.112)kPa.s/L,两者差异有统计学意义(P<0.01)。VAS表的鼻通气感觉,术前评分为7.0±2.0,术后3个月为2.5±1.5,两者间差异有统计学意义(P<0.01),患者的主客观感觉相关性好。结论:等离子射频消融治疗AR患者可取得较好的疗效,能降低其鼻黏膜的敏感性和鼻气道阻力,使患者的主观鼻通气感觉得到明显改善。

Objective：In order to explore the effect of plasma radiofrequency ablation on nasal mucosa provocative tests for allergic rhinitis.Method：Eighty patients with allergic rhinitis were enrolled in this study.The nasal mucosa provocative tests and nasal airway resistance and subjective nasal patency feeling were studied before and after plasma radiofrequency ablation treatment.The correlation of subjective and objective nasal patency was evaluated.Result： The preoperative nasal mucosa provocative test of all the patients allergic to mites were positive.The nasal mucosa provocative tests were negative within 72 patients,while remained positive in eight patients after 3 months of operation.The nasal airway resistance decreased from（0.772±0.224）kPa·s/L to（0.221±0.112）kPa·s/L after surgery（P0.01）;Visual analog scale decreased from 7.0±2.0 to 2.5±1.5 after 3 months of operation（P0.01）.Conclusion： Due to its ability to reduce the sensitivity of the nasal mucosa,nasal airway resistance and improve subjective feeling of nasal patency,plasma radiofrequency ablation is effective for the treatment of patients with allergic rhinitis.