拉米夫定治疗慢性乙型肝炎肝硬化40例分析

Lamivudine treatment of chronic hepatitis B cirrhosis:analysis of 40 cases

目的:观察拉米夫定治疗慢性乙型肝炎肝硬化的临床效果。方法:40例乙型肝炎肝硬化患者连续服用拉米夫定半年,并观察患者的治疗效果。结果:在服用拉米夫定半年后,患者HBV DNA转阴率达到75%,ALT复常率达到77%。结论:早期乙型肝炎肝硬化患者症状得到明显改善且安全,适合大范围推广和使用。代偿期乙型肝炎肝硬化患者服用拉米夫定,并密切观察患者的病情发展。

Objective To observe the clinical efficacy of lamivudine in the treatment of chronic hepatitis B cirrhosis.Methods 40 cases of liver cirrhosis of hepatitis B patients with lamivudine and to observe for the first half of the year, the therapeutic effect of patients with.Results In the patients with lamivudine after half a year, HBV DNA negative conversion rate reached 75%,the recovery rate of ALT reached 77%.Conclusion The early symptoms of patients with hepatitis B liver cirrhosis was obviously improved and safety, suitable for large-scale promotion and use. Patients with compensated cirrhosis of hepatitis B treated with lamivudine,and closely observe the patient＇s condition development.