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卵巢癌化疗的临床疗效观察 被引量:2

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摘要 选取我院2007年1月~2009年3月收治的卵巢癌患者80例,采用随机数字表法分为对照组和观察组各40例;对照组患者采用顺铂+紫杉醇联合静脉化疗;观察组患者采用紫杉醇静脉+顺铂腹腔联合化疗,疗程均为6个月;比较两组患者临床改善总有效率,1、2、3年生存率以及不良反应发生情况等。结果对照组和观察组患者临床改善总有效率组间比较无显著差异(P>0.05);观察组患者3年生存率明显高于对照组,组间比较差异显著(P<0.05);但两组患者1、2年生存率组间比较无显著差异(P>0.05);观察组患者恶心呕吐、肾功能损伤发生率明显高于对照组,组间比较差异显著(P<0.05);但两组患者腹痛腹胀、白细胞下降发生率组间比较无显著差异(P>0.05)。紫杉醇静脉与顺铂腹腔联合化疗治疗卵巢癌效果确切,可有效改善临床症状,提高生存率,且不良反应发生风险小,具有临床使用价值。
作者 桂建中
出处 《现代诊断与治疗》 CAS 2013年第4期903-904,共2页 Modern Diagnosis and Treatment
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