宁夏地区2001—2010年大肠癌患者临床特征分析

Clinical Characteristics of Colorectal Cancer in Ningxia District from the Year 2001 to 2010

目的分析宁夏地区2001—2010年大肠癌患者的临床特征。方法收集2001—2010年宁夏医科大学总医院收治的经病理证实的大肠癌患者617例,回顾性分析其临床资料,以2年为一时间段分组,记录患者的性别、发病年龄、病变部位、病理类型、Dukes分期等。结果 10年间大肠癌收治率增加了111.2%,年平均增长率为9.3%;男女发病比以2005—2006年段为拐点呈先上升后下降趋势;发病年龄以≥60岁者居多;右半结肠癌和左半结肠癌患者所占比例呈上升趋势,直肠癌患者所占比例呈锐减趋势;病理类型以中分化腺癌者居多;Dukes分期以B期者居多。结论宁夏地区2001—2010年女性大肠癌患者发病率有所升高,患者以≥60岁者居多,结肠癌患者所占比例上升,直肠癌患者所占比例下降,病理类型以中分化腺癌为主,且多为中晚期患者。

Objective To analyze the clinical characteristics of colorectal cancer in Ningxia District from the year 2001 to 2010. Methods The clinical data of 617 colorectal cancer patients admitted to this hospital from 2001 to 2010 were analyzed retrospectively. Taking 2 years as a time bucket, the patients were grouped. The gender, onset age, damaged location, patho- logical type, Dukes stage were recorded. Results The rate of patient admission increased by 111.2% during the 10 years, the annual increase rate was 9. 3%. The onset ratio of male to female was first on the rise, then on a declining curve taking 2005-- 2006 as a point of inflexion. The patients were mostly 60 years old or over. The proportion of patients with right and left colon cancer was on the rise, proportion of patients with rectum cancer on dechning curve, most pathological types were moderately dif- ferentiated, Dukes stages were mostly B stage. Conclusion In Ningxia District from 2001 to 2010, the incidence of female colorectal cancer patients has increased, mostly ≥ 60 years old; The proportion of colon cancer patients has increased, that of rectal cancer decreased; The pathological types are mostly moderately differentiated, most are mid - or advanced - term pa- tients.