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新型Ca^(2+)通道TRPV5和TRPV6的研究进展 被引量：1

Advance research on new calcium channels TRPV5and TRPV6
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摘要 TRPV5和TRPV6为瞬时感受器电位通道(TRP)的亚家族成员,是新发现的高选择性的Ca2+跨膜转运通道,其主要负责Ca2+由细胞外向细胞内的主动跨膜运输,在机体内参与多项生理活动的调节,本文作者从TRPV5和TRPV6的结构、电生理特性和调控相关因素等方面进行论述。
作者 那键 马超 霍维玲 秦瑞云 吴晓东 许永 王涛 谷贵山
机构地区 东南大学医学院附属徐州市中心医院骨关节科 吉林大学第一医院骨关节科
出处 《吉林大学学报（医学版）》 CAS CSCD 北大核心 2013年第3期634-637,共4页 Journal of Jilin University：Medicine Edition
基金 中央保健局科研基金资助课题(2006)
关键词 瞬时感受器电位蛋白Ⅴ亚家族 雌激素 骨代谢疾病
分类号 R34 [医药卫生—基础医学]
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参考文献33

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  • 4Hoenderop JG,van der Kemp AW,Hartog A,et al.Molecular identification of the apical Ca 2+channel in1,25-dihydroxy vitamin D3responsive epithelia[J].J Biol Chem,1999,274(13):8375-8378.
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  • 6Woudenberg-Vrenken TE,Lameris AL,Weibgerber P,et al.Functional TRPV6channels are crucial for transepithelial Ca 2+absorption[J].Am J Physiol Gastrointest Liver Physiol,2012,303(7):G879-G885.
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二级参考文献74

  • 1杨震,秦大明,谷贵山.新型钙通道TRPV与骨代谢的关系[J].吉林大学学报（医学版）,2005,31(4):645-648. 被引量：6
  • 2Hoenderop JG, van der Kemp AW, Hartog A, et al.Molecular identification of the apical Ca2+ channel in 1, 25-dihydroxyvitamin D3-responsive epithelia [J]. J Biol Chem, 1999, 274: 8375-8378.
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  • 4Hoenderop JG, van der Kemp AW, Hartog A, et al. The epithelial calcium channel, ECaC, is activated by hyperpolarization and regulated by cytosolic calcium [ J].Biochem Biophys Res Commun, 1999, 261: 488-492.
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  • 10Weber K, Erben RG, Rump A, et al. Gene structure and regulation of the murine epithelial calcium channels ECaCl and 2 [J]. Biochem Biophys Res Commun, 2001, 289:1287-1294.

共引文献14

同被引文献15

  • 1米永杰,李健.中药血清药理学研究概述[J].四川解剖学杂志,2006,14(4):34-35. 被引量：32
  • 2李福春,谷贵山,孙大辉,车明学,张德宝,杨震.新型钙离子通道TRPV5和TRPV6与成骨细胞信号传递的关系[J].吉林大学学报（医学版）,2007,33(3):600-603. 被引量：7
  • 3Chenard KE, Teven CM, He TC, et al. Bone morphogenetic proteins in craniofacial surgery: current techniques, clinical experiences,and the future of personalized stem cell therapy [J]. J Biomed Biotechnol, 2012,2012 : 601549.
  • 4Li W, Dunmore BJ, Morrell NW. Bone morphogenetic protein type II receptor mutations causing protein misfolding in heritable pulmonary arterial hypertensio~ [J]. Proe Am Thorac Soc, 2010,7 (6) : 395-- 398.
  • 5Conidi A, Cazzola S, Beets K, et al. Few Smad proteins and mar;y Smad--interacting proteins yield multiple functions andaction modes in TGF~/BMP signaling in vivo[J]. Cytokine Growth Factor Rev,2011,22(5/6) :287--300.
  • 6Pagani F,Francucci CM,Moro L. Markers of bone turnover.. biochemical and clinical perspectives[J]. J Endocrinol Invest, 2005,28(10 Suppl) :8--13.
  • 7Chen D, Ji X, Harris, MA, et al. Differential roles for bone morphogenetie protein (BMP) reeeptor type IB and IA indiffereniiation and specification of mesenehymal precursor cells to osteoblast and adipocyte lineages[J]. J Cell Biol, 1998,142(1) :295--305.
  • 8Hoenderop JG,Mtiller D,Van Der Kemp AW,et al. Calcitriol controls the epithelial calcium channel in kidney [J]. J Am Soc Nephrol, 2001,12(7) : 1342-- 1349.
  • 9van der Eerden BC, Hoenderop JG, de Vries TJ, et al. The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption[J]. Proc Natl Acad Sci U S A, 2005,102(48) : 17507-- 17512.
  • 10瓮媛媛,续惠云,安龙,商澎.骨样细胞MLO-Y4与成骨样细胞MC3T3-E1生物学特性的比较[J].中国细胞生物学学报,2010,32(2):261-267. 被引量：3

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二级引证文献3

吉林大学学报（医学版）
2013年 第3期

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