2型糖尿病糖化血红蛋白水平与生存质量及中医证型相关性研究

Relationship between Level of HbA1c and Quality of Life, TCM Syndrome Pattern of Patients with Type 2 Diabetes Mellitus

目的观察2型糖尿病患者糖化血红蛋白(HbA1c)水平与生存质量、中医证型的相关性。方法将255例糖尿病患者根据HbA1c水平分为血糖控制良好(HbA1c≤6.5%)、血糖控制一般(6.5%<HbA1c<7.5)、血糖控制差(HbA1c≥7.5%)3组。比较3组生存质量,并分别比较不同证型HbA1c水平。结果糖尿病不同HbA1c水平生存质量各个维度得分,除躯体角色功能外,差异无统计学意义(P>0.05)。中医证型中,脾胃气虚型及气阴两虚型之间HbA1c水平差异有统计学意义(P<0.05),其余各证型之间差异无统计学意义。结论 2型糖尿病患者HbA1c水平与生存质量、中医辨证分型有一定相关性。

Objective To observe the relationship between the level of HbA1c and quality of life（QOL）,TCM syndrome pattern of patients with type 2 diabetes mellitus（T2DM）.Methods A total of 255 cases with T2DM were divided into three groups according to the level of HbA1c：well-controlled blood glucose（HbA1c≤6.5%）,general-controlled blood glucose（6.5%HbA1c7.5）,worse-controlled blood glucose（HbA1c≥7.5%）.QOL in three groups and the level of HbA1c in different patterns of TCM syndrome were compared.Results The scores of different domains of QOL in three groups had no significant difference except the body function（P 0.05）.The level of HbA1c had significant difference between qi-yin deficiency pattern and spleen-stomach qi-deficiency pattern（P 0.05）,and no significant difference among other patterns.Conclusion The level of HbA1c in patients with T2DM is partially correlated with QOL and TCM syndrome pattern.