高龄老年高血压患者降压治疗的临床研究

Efficacy of Antihypertensive Therapy in Advanced Elder Patients with Hypertension

目的 研究高龄老年高血压患者降压治疗的效果。方法 检测350例高龄患者在降压治疗后舒张压(DBP)≥90mmHg时,70mmHg≤DBP<90mmHg及DBP<70mmHg时的血压情况、肾功能损伤情况以及心室射血分数(LEVF)。结果 高龄高血压患者进行降压治疗使舒张压达到70～90mmHg时患者血压稳定、肾损伤减少、LEVF升高(P<0.05),优于其他两组患者。结论 高龄高血压患者降血压治疗后使舒张压维持在70～90mmHg之间对患者最有利,符合J形曲线标准。

Objective To determine the efficacy of antihypertensive therapy in elder patients with hypertension. Methods 350 advanced elder hypertension patients were divided into three groups （DBP ≥90 mm Hg, 70 mm Hg ≤ DBP 90 mmHg and DBP70 mm Hg） after therapy, the blood pressure, kidney damage parameters and LEVF were all assessed. Results When the DBP decreased to 70～90 mmHg, the blood pressure keep stable, kidney damage parameters were lower and LEVF was elevated （P 0.05）, better than other two groups. Conclusion Antihypertensive therapy in advanced elder hypertension patients exhibited beneficial effects when 70 mm Hg ≤DBP 90 mm Hg, compliance with J curve.