布托啡诺复合丙泊酚静脉麻醉用于人工流产术的临床观察

The clinical observation of butorphanol combined with propol used in intrvenous anesthesia for artificial abortion

目的探讨布托啡诺复合丙泊酚用于人工流产术的安全性及有效性。方法拟行无痛人流术的健康早孕未育妇女200例,随机分为A、B两组各100例。A组:静注丙泊酚2.5 mg/kg;B组:静注布托啡诺10μg/kg+丙泊酚2.0 mg/kg;术中必要时追加丙泊酚(0.3～0.5)mg/kg。记录各组丙泊酚用药总量及麻醉相关情况。结果 B组丙泊酚用药总量明显小于A组(P<0.05);B组镇痛效果优于A组(P<0.05),同时B组不良反应较少。结论布托啡诺复合丙泊酚静脉麻醉用于人流术,麻醉效果优于单纯丙泊酚静脉麻醉,不良反应少,是一种安全有效的人工流产镇痛方法。

Objective To determine the efficacy and safety of butorphanol combined with propofol for artificial abortion. Methods A total of 200 healthy early pregnancy women were divided into two groups （n = 100 each）： Group A： intravenous injection of propofol 2.5 mg/kg; group B： intravenous injection of butorphanol l0 I.Lg/kg＋propofol2.0 mg/kg; propofo （0.3~0.5） mg/kg was used in two groups when the operation was necessary. The total amount of propofol and anesthesia related situation were recorded. Results The total amount of propofol in group B was significantly less than group A（P 〈 0.05） ;Analgesic effection of group B was superior to group A （P 〈 0.05）, and there were fewer adverse re- actions in group B. Conclusion Butorphanol combined with propofol gave better analgesic effection than simple propo- fol for artificial abortion and proned to a little adverse reaction. So butorphanol combined with propofo｜ for artificial abortion is a safe and effective intrvenous anesthesia method.