影响儿童难治性肺炎预后的危险因素及预防分析

A clinical analysis on the related risk factors of the prognosis of refractory pneumonia in children and prevention analysis

目的探讨影响儿童难治性肺炎预后的相关因素及相关预防分析。方法回顾分析48例难治性肺炎患儿的临床资料,分析可能影响患儿预后的相关临床因素。结果本组48例患儿经治疗后,最终治愈者22例(45.8%)。年龄、是否早产儿、是否低体重儿、是否合并先天性心脏病、是否合并先天性气道发育异常、是否有重症肺炎的症状及体征、并发症发生情况、住院时间均与患儿的治愈率密切相关(P<0.05)。Logistic回归结果发现年龄(OR=1.764)、是否合并先天性心脏病(OR=3.908)、是否合并先天性气道发育异常(OR=3.718)、并发症发生情况(OR=3.036)是影响患儿预后的独立危险因素。结论全面评估难治性肺炎患儿的高危因素,给予相应辅助预防方案,对提高患儿的治愈率、改善预后具有重要的临床意义。

Objective To analyze the related risk factors of the prognosis of refractory pneumonia in children and pre- vention analysis. Methods 48 cases who was diagnosed as refractory pneumonia in children were analyzed with retro- spective cohort study. Univariate and multivariate analysis were performed for possible factors related to the prognosis of refractory pneumonia in children. Results Among the 48 refractory pneumonia in children,there were 22 cases cured （45.8%）. The age, premature, low-birth weight infant,congenital heart disease, abnormity of respiratory tract, se- vere pneumonia, complications,hospital stays were related factors of the prognosis of refractory pneumonia in children （P 〈 0.05）. Prognostic risk factors were as follows：age with OR = 1.764,congenital heart disease with OR = 3.908 ,ab- normity of respiratory tract with OR = 3.718, complications with OR = 3.036. Conclusion Early diagnosis, assessing risk factors and treatment for each refractory pneumonia in children are be important to increase the rate of cure and to improve the prognosis of refractory pneumonia in children.