不同胰岛素注射液在糖尿病治疗中的应用研究

The Study of Difference of Insulin Injection in Treating Diabetes

目的探讨不同胰岛素注射液在糖尿病患者的治疗中的使用和治疗效果。方法回顾性分析2009年1月—2011年6月我院收治的600例糖尿病患者的临床资料,根据采用治疗的胰岛素的不同将患者分为3组,每组各200例。其中A组采用甘精胰岛素治疗,B组使用精蛋白锌重组人胰岛素混合注射液治疗,C组采用动物源胰岛素治疗。观察三组患者的血糖水平、血糖达标时间、胰岛素日用量及低血糖发生率。结果治疗后3组患者空腹血糖、餐后2h血糖、血糖达标时间、胰岛素日用量及低血糖发生率比较,差异均有统计学意义(P<0.05)。结论使用甘精胰岛素能够起到较好的血糖控制作用,胰岛素用量少,减少低血糖的发生率,有效改善B细胞功能,是治疗糖尿病的良好方法。

Objective To disucss the difference of effect and use of insulin Injection in treating diabetes. Methods Choosed 600 diabetes patients from Jan.2009 to Jun.2011 to divide into three groups with 200 cases in each other.A group were treated with insulin glargine,B group were treated with protamine zinc recombinant human insulin,C group were treated with animal source insulin.Compared the clinical changing and B cell function change. Results There was no difference in dosage of these kinds of insulins.And the lowest incidence of hypoglycemia and shortest blood sugar therapeutic time was A group. Conclusion Using insulin glargine could controll blood sugar well with less dosage and lower incidence of hypoglycemia to improve function of B cell.