急性脑梗死与高同型半胱氨酸血症相关性分析

Acute Cerebral Infarction with Hyperhomocysteinemia Correlation Analysis

目的:探讨急性脑梗死与血浆高同型半胱氨酸(Hcy)血症的关系。方法:选取75例急性脑梗死住院患者和45例同期正常的健康体检者进行血浆Hcy、叶酸和维生素B12的测定,并进行比较。结果:急性脑梗死组患者血浆Hcy水平明显升高,叶酸、维生素B12水平明显低于对照组(P<0.05)。结论:急性脑梗死组患者血浆Hcy升高,而叶酸、维生素B12下降,高同型半胱氨酸血症是急性脑梗死的独立危险因素之一。

Objective：To explore the acute cerebral infarction and plasma homocysteine （ Hcy ） in relation. Methods： 75 cases of acute cerebral infarction patients and compared with 45 normal healthy subjects underwent plasma Hcy, folic acid and vitamin B12 were determined, and compared. Results： the plasma Hcy level in patients with acute cerebral infarction group was significantly elevated, folate, vitamin B12 levels were significantly lower than those in control group （ P0.05 ）. Conclusion： acute cerebral infarction patients plasma Hcy increased, and folic acid, vitamin B12 drops, hyperhomocysteinemia is an independent risk factor for acute cerebral infarction.