期刊文献+

吡格列酮对2型糖尿病患者血清C反应蛋白影响的分析

原文传递
导出
摘要 目的:观察吡格列酮治疗2型糖尿病及对血清C反应蛋白的影响。方法:将初诊的2型糖尿病患者190例随机分组为治疗组(86例)和对照组(104例)。在饮食控制及运动治疗基础上,对照组予胰岛素强化治疗,治疗组在强化治疗基础上加用吡格列酮。治疗6个月前后查空腹血糖(FPG)、餐后2小时血糖(2hPG)、糖化血红蛋白(HbA1c)及甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、超敏C反应蛋白(hs-CRP)。结果:2组治疗后FPG、2h小时PG、HbA1c、TG、TC、HDL-C、LDL-C、hs-CRP水平明显改善,治疗前后有统计学意义(P<0.05)。且治疗后治疗组的HbA1c、血脂、hs-CRP改善显著优于对照组,差异有统计学意义(P<0.05)。结论:吡格列酮可降低2型糖尿病患者血糖、血脂水平,降低血管炎性反应,可于临床广泛应用。
出处 《中国伤残医学》 2013年第5期217-218,共2页 Chinese Journal of Trauma and Disability Medicine
  • 相关文献

参考文献3

二级参考文献20

  • 1成兴波,范庆涛.2型糖尿病合并高血压患者抵抗素与动脉粥样硬化的相关性研究[J].标记免疫分析与临床,2006,13(4):215-217. 被引量:8
  • 2Volanakis JE. Human C reactive protein: expression structure and ruction[J]. Mol Immunol, 2001, 38:189.
  • 3Ridney PM, Cushman M, Meir J, et al. Inflammation, aspirin and the risk of cardio vaeular disease in apparently healthy men [J]. N EnglJ Med, 1997, 336:973-979.
  • 4Pickup JC, Mattock MB, chusney GD, et al. NIDDM Masa disease of innate immune system: association of acute yeaetants and interleuk in 6 with metabolic syndrone X[J]. Diabetology, 1997,40;1286-1292.
  • 5Tsirpanlis G, Chatzipangiotou S, Nicolaou C, et al. Microinflammation versus inflammation in chronic renal failure patients[J]. Kid Int, 2004, 66:2093-2098.
  • 6Mendall MA, Patet P, Ballam L, et al. C-reactive protein and its relation to cardiovascular risk factors: a population based cross section study[J]. BMJ, 1996, 312 : 1061-1065.
  • 7Grau AJ, Buggle H. The association of leucocyte count, fibroinogen and C-reactive protein with vascular disease [J]. Thromb Res, 1996, 82:245.
  • 8Juhan-Vague I, Thompson SG, Jespersen J. Involvement of the hemostatic system in the insulin resistance syndrome: a study of 1600 patients with angina peetoris: the ECAT Angina Pectoris Study Group [J]. Arterioscler Thromb, 1993, 13: 1865-1873.
  • 9Stefanadi E,Tousoulis D,Papageorgiou N,et al.Inflammatory Biomarkers Predicting Events in Atherosclerosis[J].Curr Med Chem,2010,Mar 26.[Epub ahead of print].
  • 10Stofkova A.Resistin and visfatin:regulators of insulin sensitivity,inflammation and immunity[J].Endocr Regul,2010,44:25-36.

共引文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部