摘要
耐辐射异常球菌对各种DNA损伤均有极好的抗性,该菌选择不同的DNA修复途径来应对清除不同DNA损伤,包括直接DNA反转、碱基和核苷酸切除修复、错配修复和重组修复等。本文对耐辐射异常球菌中重要的同源重组修复系统进行了综述。
Deinococcus radiodurans is extremely resistant to various DNA-damaging. The diversity of DNA damage withstood by D. radiodurans is commensurate with the selection of DNA repair pathways at its disposal： direct damage reversal, base and nucleotide excision repair, mismatch repair, and recombinational repair. In this article, we have tried to bring information together to give a broad perspective of DNA repair systems in D. radiodurans.
出处
《生物技术进展》
2013年第3期171-178,I0003,I0003,共10页
Current Biotechnology
基金
国家自然科学基金项目(31170105)
农业部公益性行业科研专项(201103007)
国家转基因生物新品种培育重大专项(2013ZX08012-001
2013ZX08009-003)
国家863计划项目(2012AA063503)资助
关键词
耐辐射异常球菌
切除修复
错配修复
重组修复
Deinococcus radiodurans
excision repair
mismatch repair
recombinational repair
