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符合线路SPECT-^(18)FDG显像诊断肺癌的研究 被引量:5

A Study of ^(18)FDG imaging with coincidence SPECT for the diagnosis of lung cancer
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摘要 用双探头ECT进行^(18)FDG符合线路显像,探讨对肺癌的诊断价值。 39例未确诊的肺部病变患者,禁食4h静脉注入37-111MBq^(18)FDG。静休1-2h在胸部行断层显像,用叠代法重建。检测病灶区与对侧对照区核素的浓聚比值,超过1.3为显像阳性。根据显像结果对肺癌诊断的灵敏度是93%(25/27),特异性83%(10/12),符合率90%(35/39)。本显像技术对肺癌诊断有较好的应用价值。 SPECT coincidence imaging was performed on a dual-head gamma camera (DST-XLi, SMV) to allow the detection of 511keV gamma emission of ^(18)FDG positron radionuclides. ^(18)FDG was provided by Shanghai Institute of Nuclear Research. All the patients with lung lesions on X-ray film have not yet confirmed in diagnosis underwent ^(18)FDG imaging. Patients fasted 4 hours before administration of ^(18)FDG and kept rest from 1-2 hours after intravenous administration of 37-111MBq ^(18)FDG. Images were reconstructed by lterative reconstruction. Draw ROI on lesion area (L) and control area (C). The L/C ratio larger than 1.3, it was considered positive. Of total 39 cases, the sensitivity, specificity and accuracy was 93%(25/27), 83%(10/12) and was 90%(35/39) respectively, for the diagnosis of lung cancer. Therefore coincidence imaging of ^(18)FDG-SPECT is a suitable and reliable new technology for the diagnosis of lung cancer.
机构地区 上海市肺科医院
出处 《核技术》 CAS CSCD 北大核心 2000年第5期305-307,共3页 Nuclear Techniques
关键词 SPECT 肺癌 诊断 氧-18 同位素诊断 ^(18)FDG imaging, Coincidence SPECT, Lung cancer
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参考文献3

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同被引文献36

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