肝硬化并发自发性细菌性腹膜炎患者发病危险因素分析

Risk factors associated with spontaneous bacterial peritonitis in liver cirrhotic patients

目的探讨肝硬化并发自发性细菌性腹膜炎(SBP)的发病危险因素。方法连续收集2008年1月至2010年12月间在惠州市中心人民医院及惠州市第一人民医院住院确诊为肝硬化合并SBP的206例病例。对可能影响肝硬化患者发生SBP的危险因素进行单因素分析,将有意义的因素纳入Logistic回归模型进行多因素分析。结果MELD评分,脾脏厚度和腹水总蛋白最终进入了Logistic回归方程,OR分别为4.703、3.864、7.108。结论 MELD评分、脾脏厚度、腹水总蛋白可能为SBP发生的独立危险因素。

Objective To investigate the risk factors associated with spontaneous bacterial peritonitis（SBP）in liver cirrhotic patients.Methods The risk factors associated with SBP in 206 liver cirrhosis cases diagnosed in Huizhou Municipal People＇s Hospital and Huizhou Municipal Central Hospital in the January 2008 to December 2010.were analyzed and the Univariate analysis was used to investigate risk factors associated with SBP in liver cirrhosis patients,then the meaningful factors were analyzed by using multivariate logistic regression model.Results The OR value of MELD score,spleen thickness and total protein in ascites as calculated with logistic regression equation were 4.703,3.864,7.108...Conclusions MELD score,spleen thickness and total protein in ascites might be the independent risk factors associated with SBP in liver cirrhosis patients..