益生菌联合西替利嗪治疗儿童慢性荨麻疹疗效观察

Therapeutic effect of probiotics combined with cetirizine on chronic urticaria in children

目的:探讨益生菌—思连康联合盐酸西替利嗪对慢性荨麻疹患儿疗效和安全性。方法:66例慢性荨麻疹患儿随机进入观察组和对照组:观察组,34例,盐酸西替利嗪滴剂,1mL,口服,1次/d;同时加用思连康片1g,3次/d,共14d;对照组,32例,盐酸西替利嗪滴剂,1mL,口服,1次/d,共14d。治疗2周后进行疗效评价。结果:观察组有效率88.2%,对照组有效率62.5%,两组比较差异有统计学意义(P<0.05);且均无明显不良反应。结论思连康联合西替利嗪治疗儿童慢性荨麻疹短期疗效较高,安全性高。

Objective To explore curative effect and safety of Siliankang combined with cetirizine hydrochloride on child chronic urticaria patients. Methods The 66 children with chronic urticaria were randomly divided into observation group（34 cases）treated with cetirizine hydrochloride drops,1mL,P.O,Qd;at the same time combined with Si Lian Kang 1g,P.O,Tid,total of 14 days and control group（32 cases） treated with only with cetirizine hydrochloride drops,1mL,P.O,Qd,for a course of 14 days.The results in both groups were evaluated two week later. Results The effective rate was 88.2% in the observation group and 62.5% in the control group,showing significant difference between two groups（P0.05）.And there were no obvious adverse reactions in the observation group. Conclusion Short-term curative effect of Shiliankang combined with cetirizine is safe and highly effective on child chronic urticaria.