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色素上皮衍生因子在银屑病中的表达及意义

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摘要 目的:检测色素上皮衍生因子(PEDF)在银屑病中的表达。方法:采用免疫组化和RTPCR法检测20例银屑病皮损及20例正常皮肤组织中PEDF蛋白和mRNA的表达。结果:银屑病皮损中PEDF蛋白和mRNA的表达水平明显高于对照组,差异有统计学意义。结论:银屑病皮损中PEDF蛋白和mRNA的表达水平上调,可能参与银屑病的发病过程。
作者 田诗姣 董宇昊 张岩 冯子超 毛新荷 马伟元
机构地区 山东大学医学院 山东大学齐鲁医院皮肤科
出处 《中国麻风皮肤病杂志》 2013年第5期321-324,共4页 China Journal of Leprosy and Skin Diseases
关键词 银屑病 色素上皮衍生因子 表达 免疫组织化学 反转录PCR
分类号 R758.63 [医药卫生—皮肤病学与性病学]
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参考文献15

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中国麻风皮肤病杂志
2013年 第5期

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