重新评价甲苯咪唑 ( Vermox)治疗囊型包虫病的效果(摘要 )(英文)

Reappraisal of Mebendazole (Vermox) Efficacy for Treatment of Cystic Echinococcosis

本文报道了临床观察甲苯咪唑 ( Vermox,由比利时杨森制药公司提供 )治疗 12例囊型包虫病的效果。12例病人中 ,肝包虫 6例 ,肺包虫 4例 ,肝—肺包虫 2例。成人每次口服剂量 5 0 0 mg,t.i.d.,小儿酌减。1疗程 30天 ,至少服 3疗程 ,治疗前后作影像检查对比 ,肝包虫作 B超检查 ,肺包虫拍 X线胸片。结果 12例中治愈 2例 ( 16 .7% ) ,改善 8例 ( 72 .6 % ) ,无效 2例 ( 16 .7% ) ,均未发生任何副反应。从而提示

This paper observed clinically the efficacy of mebendazole (Vermox) in the treatment of 12 cases with cystic echinococcosis (CE). Among 12 cases, 6 were liver CE, 4 lung CE, and 2 liverlung CE. The daily dose was 500 mg one time t.i.d.. in adults and decreased appropriately in children. One therapeutic course lasted 30 days and at least three courses were administered in this series. A comparision of the imaging examinations was made between pre and posttreatment. Chest Xray film and ultrasonic scanning were adopted respectively in lung CE and in liver CE. Out of 12 cases, 2 were cured (16.7%), 8 improved (72.7%), and 2 failed (16.6%). Any side reactions was not found in every patient. The above results showed that mebendazole (Vermox) was still an effective drug in the treatment of cystic echinococcosis.