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聚乙二醇在脂质体中的作用 被引量:3

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摘要 兼有亲水性和柔顺性的聚乙二醇高分子,能在脂质体表面形成一层水化膜,阻碍血浆成分与脂质体表面的吸附,从而降低网状内皮系统对脂质体的摄取,使脂质体在体循环中的时间延长。本文从作用机理角度,综述聚乙二醇对脂质体及免疫脂质体的稳定性和药物动力学的影响,以及其在脂质体中的应用。
出处 《国外医药(合成药.生化药.制剂分册)》 2000年第3期178-81,共1页 World Pharmacy
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参考文献10

  • 1Woodle MC,Lasic DD. Biochimica et Biophysica Acta . 1992
  • 2Moghimi SM,Patel HM. FEBS Letters . 1988
  • 3Moghimi SM,Patel HM. Biochimica et Biophysica Acta . 1989
  • 4Blume G,Cevc G. Biochimica et Biophysica Acta . 1990
  • 5Senior J,Deigado C,Fisher D et al. Biochimica et Biophysica Acta . 1991
  • 6Bradley Al,Devine DV,Ansell SM et al. Archive of Biochemistry and Biophysics . 1998
  • 7Blume G,Cevc G. Biochimica et Biophysica Acta . 1993
  • 8Mori A,Klibanov AL,Torchilin VP et al. FEBS Letters . 1991
  • 9Tirosh O,Barenholz Y,Katzhendler J et al. Biophysical Journal . 1998
  • 10Torchilin VP,Omelyanenko VG,Papisov IM et al. Biochimica et Biophysica Acta . 1994

同被引文献44

  • 1孙燕妮,李强,刘忠令.光动力疗法对人肺腺癌细胞系A549凋亡的影响[J].第二军医大学学报,2004,25(7):729-732. 被引量:1
  • 2张林,王先升.光动力疗法在恶性实体瘤治疗中的应用[J].山东医药,2004,44(20):66-67. 被引量:2
  • 3沙卫红,李瑜元,聂玉强,周永健,黎庆宁,王红,梁培智,赖晓波,佘庆珠,吴惠生.光动力疗法治疗进展期消化道肿瘤的疗效观察[J].中国综合临床,2005,21(2):124-126. 被引量:9
  • 4曾凡彬,陆彬,杨红,邓希贤.盐酸川芎嗪肺靶向微球的研究[J].药学学报,1996,31(2):132-137. 被引量:50
  • 5Schneider T, Sachse A, Roessling G, et al. Generation of contrast-carrying liposomes of defined size with a new continuous high pressure extrusion method[J]. Int J Pharm, 1995, 117(1):1-12.
  • 6Sivakumar PA, Rao KP. Polymerized (ethylene glycol) dimethacrylate-cholesteryl methacrylate liposomes: preparation and stability stuides[J]. Reative & Functional Polymers, 2001, 49(3):179-187.
  • 7Takeuchi H, Yamamoto H, Toyoda T, et al. Physical stability of size controlled small unilamellar liposomes coated with a modified poly(vinyl alcohol)[J]. Int J Pharm, 1998, 164(1-2):103-111.
  • 8Kayalar C, Duzgunes N. Membrane action of colicin E1:detection by the release of carboxyfluorescein and calcein from liposomes [J]. Biochim Biophys Acta,1986, 860(1):51-56.
  • 9Mercadal M, Domingo JC, Bermudez M, et al. N-Palmitoylphosphatidylethanolamine stabilizes liposomes in the presence of human serum: effect of lipidic composition and system characterization [J].Biochim Biophys Acta, 1995, 1235(2) :281-288.
  • 10Mrsny R J, Volwerk J J, Griffith OH. A simplified procedure for lipid phosphorus analysis shows that digestion rates vary with phospholipid structure[J].Chem Phys Lipids, 1986, 39(1-2) : 185-191.

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